Darunavir Simvastatin 943

Prezista label

Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for increased levels of simvastatin
Drug 1
Drug 1 effect

Not studied

Drug 2
Drug 2 effect

Not studied (may increase simvastatin levels)

Clinical Effects

Increased risk of simvastatin adverse effects (e.g. myopathy, rhabdomyolysis)

Management

Contraindicated. Use alternative agents.

Alternative Agents
Atorvastatin (low dose)
Import ID
943