Darunavir HMG-CoA Reductase Inhibitors 939

Prezista label

Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for increased levels of lovastatin
Drug 1
Drug 1 effect

Not studied

Drug 2
Drug 2 effect

Not studied (may increase lovastatin levels)

Clinical Effects

Increased risk of lovastatin adverse effects (e.g. myopathy, rhabdomyolysis)

Management

Contraindicated. Use alternative agents.

Alternative Agents
Atorvastatin (low dose)
Import ID
939