Prezista label
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid decreased levels of omeprazole
Drug 1
Drug 1 dose
600 mg with 100 mg ritonavir BID
Drug 1 effect
No significant change
Drug 2
Drug 2 dose
40 mg x 1
Drug 2 effect
Cmax decrease 34%, AUC decrease 42%
Clinical Effects
Potential decreased omeprazole efficacy
Management
Consider using alternative agents. If coadministering, monitor for omeprazole efficacy. If no symptomatic relief, increase dose to no more than 40 mg once daily
Import ID
869
