Darunavir Canagliflozin 867

Prezcobix label

Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid decreased levels of canagliflozin
Drug 1
Drug 2
Clinical Effects

Potential for decreased glucose lowering effect

Management

If a patient is already tolerating canagliflozin 100 mg daily, increase canagliflozin dose to 200 mg daily. If a patient is already tolerating canagliflozin 200 mg daily and requires additional glycemic control, management strategy is based on renal function, 300 mg if eGFR>60 or add another agent if eGFR<60

Import ID
867