Atazanavir RIF 838

Reyataz label

Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of atazanavir
Drug 1
Drug 1 dose
300 mg with 100 mg ritonavir daily x 21 d
Drug 1 effect

Atazanavir AUC decreased 72%, Cmax decreased 53%, Cmin decreased 98%

Drug 2
Drug 2 dose
600 mg daily x 10 d
Drug 2 effect

Not reported

Clinical Effects

Potential loss of antiretroviral efficacy

Management

Contraindicated. Use alternative agents.

Alternative Agents
Rifabutin
Import ID
838