Reyataz label
Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of atazanavir
Drug 1
Drug 1 dose
300 mg with 200 mg ritonavir daily x 10 d
Drug 1 effect
Atazanavir AUC decreased 31%, Cmax decreased 40%, Cmin decreased 80%(compared to atazanavir 400 mg daily)
Drug 2
Drug 2 dose
600 mg daily x 10 d
Drug 2 effect
Not reported
Clinical Effects
Potential loss of antiretroviral efficacy
Management
Contraindicated. Use alternative agents.
Alternative Agents
Rifabutin
Import ID
836
