Reyataz label
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of methadone
Drug 1
Drug 1 dose
400 mg daily on d 2-15
Drug 2
Drug 2 dose
stable dose on d 1-15
Drug 2 effect
Total methadone Cmax decresed 15%
Clinical Effects
Potential decreased methadone effects (withdrawl, inadequate pain control, cravings)
Management
If coadministering monitor for signs and symptoms of methadone withdrawal. Some patients may require an increased methadone dose
Import ID
801
