Atazanavir RFB 768

Reyataz label

Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of rifabutin
Drug 1
Drug 1 dose
400 mg daily on days 1-28
Drug 1 effect

Atazanavir Cmax increased 34%

Drug 2
Drug 2 dose
150 mg daily on days 15-28
Drug 2 effect

Not reported

Management

Use rifabutin 150 mg once daily or 300 mg three times a week. Monitor for antimycobacterial activity and consider therapeutic drug monitoring.

Import ID
768