Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
10 mg once daily
Drug 1 effect
Cmax decreased 20%, AUC decreased 13%
Drug 2
Drug 2 dose
400 / 100mg once daily
Drug 2 effect
Sofosbuvir: Cmax increased 23%, AUC increased 37%; Sofosbuvir metabolite: Cmax increased 29%, AUC increased 48%, Cmin increased 58%; velpatasvir: Cmax increased 30%, AUC increased 50%, Cmin increased 60%
Import ID
715
