Nevirapine SQV 638

Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 1 dose
200 mg daily x 14 days
Drug 1 effect

Not studied

Drug 2
Drug 2 dose
600 mg (hard gel caps) TID
Drug 2 effect

Saquinavir AUC decreased 24%; Cmax decreased 28%

Clinical Effects

Decreased saquinavir effects

Management

Use alternative agents

Import ID
638