Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of ketoconazole
Drug 1
Drug 1 dose
200 mg daily x 14 days; 200 mg BID x 14 days
Drug 2
Drug 2 dose
400 mg daily
Drug 2 effect
Ketoconazole AUC decreased 72%; Cmax decreased 44%
Clinical Effects
Decreased ketoconazole effects
Management
Use alternative agents
Import ID
618
