Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for reduced levels of elbasvir / grazoprevir
Drug 1
Drug 1 dose
200 mg BID
Drug 1 effect
Nevirapine AUC decreased 31%; Cmax decreased 36%; Cmin decreased 21%
Drug 2
Drug 2 effect
Not studied (may decrease grazprevir levels)
Clinical Effects
Decreased elbasvir, grazoprevir levels expected
Management
Contraindicated. Use alternative agents.
Import ID
606
