Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
200 mg BID
Drug 1 effect
Nevirapine AUC increased 110%; Cmax increased 115%; Cmin increased 135%; half-live: decreased 52% (data compared to historical controls)
Drug 2
Drug 2 dose
400 mg BID with ritonavir 100 mg BID
Drug 2 effect
Darunavir AUC increased 24%; Cmax increased 40%
Clinical Effects
Potential for increased darunavir effects; Potential for increased nevirapine effects
Import ID
597
