Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of fosamprenavir
Drug 1
Drug 1 dose
200 mg BID
Drug 1 effect
Nevirapine AUC decreased 46%; Cmax decreased 42%
Drug 2
Drug 2 dose
1400 mg BID
Drug 2 effect
Fosamprenavir AUC decreased 33%; Cmax decreased 25%; Cmin decreased 35%
Clinical Effects
Decreased fosamprenavir effects
Management
Do not use with fosamprenavir alone. Ritonavir boosted fosamprenavir (700 / 100 mg BID) can be considered
Alternative Agents
Consider ritonavir-boosted fosamprenavir
Import ID
577
