Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 1 dose
600 mg QHS
Drug 2
Drug 2 dose
100 mg with 250 mg atovaquone x 1
Drug 2 effect
Proguanil AUC decreased 43%; Cmax no significant change
Management
Consider using alternative agents. If coadministering, dose adjustment not established
Import ID
494
