Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: risks likely to outweigh benefits
Drug 1
Drug 1 effect
Not studied (may decrease efavirenz levels)
Drug 2
Drug 2 effect
Not studied (may decrease phenytoin levels)
Clinical Effects
Decreased efavirenz and phenytoin effects
Management
Avoid combination and use alternative agents. If coadministering, \monitor phenytoin levels and adjust as indicated
Alternative Agents
Gabapentin Lamotrigine Tiagabine Topiramate
Import ID
485
