Efavirenz Saquinavir 469

Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction, weigh risks and benefits of using this combination
Drug 1
Drug 1 dose
600 mg daily for 10 days
Drug 2
Drug 2 dose
1200 mg every 8 hours for 10 days
Drug 2 effect

AUC decreased 62%, Cmin decreased 56%, Cmax decreased %50

Clinical Effects

Potential loss of antiviral efficacy

Management

Use alternative agents

Import ID
469