Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of levonorgestrel
Drug 1
Drug 1 dose
600 mg QHS
Drug 2
Drug 2 dose
0.75 mg x 1
Drug 2 effect
Levonorgestrel AUC decreased 64%; Cmax decreased 45%; Cmin decreased 71%; half-life: decreased 47%
Clinical Effects
Decreased levonorgestrel effects
Management
Use alternative contraceptive method
Import ID
451
