Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for reduced levels of atazanavir
Drug 1
Drug 1 dose
600 mg daily days 11-24
Drug 2
Drug 2 dose
300 mg daily / ritonavir 100 mg daily days 1-10 then 400 mg daily / ritonavir 100 mg daily days 11-24
Drug 2 effect
Atazanavir Cmin decreased 42%, Cmax increased 17%
Clinical Effects
Potential loss of antiviral efficacy
Management
Use alternative agents
Import ID
438
