Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for reduced levels of atazanavir
Drug 1
Drug 1 dose
600 mg daily days 7-20
Drug 2
Drug 2 dose
400 mg daily x 20 days
Drug 2 effect
Atazanavir AUC decreased 74%, Cmax decreased 59%, Cmin decreased 93%.
Clinical Effects
Potential loss of antiviral efficacy
Management
Use alternative agents
Import ID
435
