Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg daily
Drug 2
Drug 2 dose
Ledipasvir 90 mg with sofosbuvir 400 mg daily
Drug 2 effect
Ledipasvir AUC, Cmin, Cmax all decreased 34%; Sofosbuvir: no significant effect
Import ID
414
