Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg x 10 days
Drug 1 effect
Efavirenz AUC increased 21%; Cmax no significant change
Drug 2
Drug 2 dose
500 mg Q12H x 8 days
Drug 2 effect
Ritonavir AUC increased 18% after AM dose; Cmax increased 24% after AM dose; AUC no significant change after PM dose; Cmax no significant change after PM dose
Clinical Effects
Increased efavirenz and ritonavir effects
Import ID
409
