Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg daily on days 4-18
Drug 1 effect
No significant change
Drug 2
Drug 2 dose
10 mg daily on days 0-3 and 15-18
Drug 2 effect
Atorvastatin AUC decreased 43%; Atorvastatin and metabolites AUC decreased 34%
Clinical Effects
Decreased lipid effects
Management
Monitor for statin efficacy. May need to increase atorvastatin dose
Import ID
406
