Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg daily x 14 days
Drug 1 effect
No significant change
Drug 2
Drug 2 dose
240 mg daily x 21 days
Drug 2 effect
Diltiazem AUC decreased 69%; Cmax decreased 60%; Cmin decreased 63%
Clinical Effects
Decreased diltiazem effects
Management
Monitor diltiazem efficacy and to titrate to clinical effect
Import ID
389
