Efavirenz MVC 364

Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of maraviroc
Drug 1
Drug 1 dose
600 mg daily
Drug 2
Drug 2 dose
100 mg BID
Drug 2 effect

Maraviroc AUC decreased 45%; Cmax decreased 51%; Cmin decreased 45%

Clinical Effects

Decreased maraviroc effects

Management

Increase maraviroc dose to 600 mg BID

Import ID
364