Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of doravirine
Drug 1
Drug 1 dose
100 mg x 1
Drug 1 effect
AUC decreased 62%; Cmax decreased 35%; C24 decreased 85%
Drug 2
Drug 2 dose
600 mg x 1
Drug 2 effect
Not studied
Clinical Effects
Potential decrease in antiretroviral efficacy
Management
Do not coadminister. Use alternative agents.
Import ID
359
