Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of doravirine
Drug 1
Drug 1 dose
100 mg
Drug 1 effect
AUC decreased 32%; Cmax decreased 14%; C24 decreased 50%
Drug 2
Drug 2 dose
600 mg daily x 14 days
Drug 2 effect
Not studied
Clinical Effects
Potential decrease in antiretroviral efficacy
Management
Do not coadminister. Use alternative agents.
Import ID
358
