Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid reduced levels of raltegravir
Drug 1
Drug 1 dose
400 mg BID
Drug 1 effect
Raltegravir AUC increased 73%; Cmax increased 89%; Cmin decreased 44%
Drug 2
Drug 2 dose
900 mg PO once weekly
Management
When coadministering with once weekly rifapentine use raltegravir 400 mg BID. Do not coadminister raltegravir with once daily rifapentine.
Import ID
284
