Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 2
Clinical Effects
Potential for increased risk of quetiapine adverse effects
Management
Consider alternative ARV therapy. For patients currently on elvitegravir / cobicistat: initiate quetiapine at lowest dose. Titrate accordingly and monitor for adverse effects. If patient already on quetiapine and requiring new elvitegravir / cobicistat: reduce queitapine to 1 / 6 of original dose before coadministering. Monitor efficacy and adverse effects.
Import ID
234
