Interaction Color Code
Clinical Bottom Line
Do not coadminister: Potential for increased levels of midazolam
Drug 1
Drug 2
Clinical Effects
Potential for increased alprazolam effects (e.g. sedation, altered mental status, respiratory depression)
Management
Coadministration of EVG with oral midazolam is contraindicated. Parenteral midazolam can be used with caution when given as a single dose in a closely monitored situation for procedural sedation.
Alternative Agents
Lorazepam, Oxazepam, Temazepam
Import ID
194
