Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
150 mg elvitegravir / 150 mg cobicistat once daily
Drug 1 effect
If omeprazole given 2 hours before EVG, Cmax increased 16%, AUC increased 10%, Cmin increased 13%. If given 12h after, no significant change.
Drug 2
Drug 2 dose
20 mg given 2 hours before or 12 hours after elvitegravir
Drug 2 effect
Not reported
Import ID
133
