Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
150 mg elvitegravir / 150 mg cobicistat once daily
Drug 1 effect
Not reported
Drug 2
Drug 2 dose
4-6 mg once daily
Drug 2 effect
Cmax and AUC decrease 28%
Clinical Effects
Potential reduced efficacy of naloxone
Import ID
130
