Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
50 mg single dose
Drug 1 effect
Cmax increased 22%, AUC increased 16%, Cmin increased 14%
Drug 2
Drug 2 dose
elbasvir 50 mg + grazoprevir 200 mg once daily
Drug 2 effect
No significant change in elbasvir. Grazoprevir Cmax decreased 36%, AUC decreased 19%, Cmin decreased 14%
Import ID
105
