Interaction Color Code
Clinical Bottom Line
Minimal data to guide interaction: weigh risks and benefits of using this combination
Drug 1
Drug 1 dose
75mg single dose
Drug 1 effect
Cmax increased 9%, AUC increased 61%
Drug 2
Drug 2 dose
300 mg BID (fasted state)
Drug 2 effect
Not reported
Clinical Effects
Potentially increased bictegravir adverse effects
Management
Consider using alternative agents; if coadministering, monitor for bictegravir adverse effects
Import ID
83
