Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
50 mg once daily
Drug 1 effect
Cmax decreased 2%, AUC increased 7%, Cmin increased 10%
Drug 2 dose
400 / 100 / 100 + 100 voxilaprevir once daily (fed state)
Drug 2 effect
Sofosbuvir Cmax increased 14%, AUC increased 9%. Velpatasvir Cmax decreased 4%, AUC decreased 4%, Cmin decreased 6%. Voxilaprevir Cmax decreased 10%, AUC decreased 9%, Cmin decreased 3%
Import ID
70
