Bictegravir LDV/SOF 69

Interaction Color Code

Clinical Bottom Line

Administer standard doses

Drug 1

Drug 1 dose

75 mg once daily

Drug 1 effect

Cmax decreased 2%, Cmin increased 4%

Drug 2

Drug 2 dose

90 / 400 mg once daily

Drug 2 effect

Ledipasvir Cmax decreased 15%, AUC decreased 13%. Sofosbuvir Cmax increased 11%, AUC increased 7%

Import ID