Selzentry package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of maraviroc
Drug 1
Drug 1 dose
300 mg daily
Drug 1 effect
Maraviroc Cmin increased 16%; Cmax no significant change (when compared to maraviroc 300 mg BID without darunavir / ritonavir in separate control arm)
Drug 2
Drug 2 dose
800 / 100 mg BID
Drug 2 effect
Not reported
Management
Reduce dose of maraviroc to 150 mg BID
Import ID
49
