Selzentry package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid decreased levels of maraviroc
Drug 1
Drug 1 dose
300 mg BID
Drug 1 effect
Maraviroc AUC decreased 53%; Cmin decreased 39%
Drug 2
Drug 2 dose
200 mg BID
Drug 2 effect
Not reported
Clinical Effects
Potential decrease in antiretroviral efficacy
Management
Increase maraviroc dose to 600 mg BID. If including MVC, ETR plus a strong CYP3A4 inhibitor in the regimen, reduce maraviroc dose to 150 mg BID
Import ID
38
