Selzentry package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid decreased levels of maraviroc
Drug 1
Drug 1 dose
100 mg BID
Drug 1 effect
Maraviroc AUC decreased 45%; Cmax decreased 51%
Drug 2
Drug 2 dose
600 mg daily
Drug 2 effect
Not reported
Clinical Effects
Potential decrease in antiretroviral efficacy
Management
Increase maraviroc dose to 600 mg BID. If including MVC, EFV plus a strong CYP3A4 inhibitor in the regimen, reduce maraviroc dose to 150 mg BID
Import ID
35
