Selzentry package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid decreased levels of maraviroc
Drug 1
Drug 1 dose
200 mg BID
Drug 1 effect
Maraviroc AUC increased 4%; Cmax decreased 3% when compared to maraviroc 100 mg BID given alone.
Drug 2
Drug 2 dose
600 mg daily
Drug 2 effect
Not reported
Management
Increase maraviroc dose to 600 mg BID. If also including a strong CYP3A4 inhibitor in the regimen, consider using an alternative agent due to difficulty predicting maraviroc concentrations.
Import ID
34
