Rukobia package insert
Interaction Color Code
Clinical Bottom Line
Do not coadminister: Reduced levels of temsavir
Drug 1
Drug 1 dose
1200 mg once daily
Drug 1 effect
Temsavir Cmax decreased 76%, AUC decreased 82%
Drug 2
Drug 2 dose
600 mg once daily
Drug 2 effect
Not reported
Clinical Effects
Potential decrease in antiretroviral efficacy
Management
Contraindicated. Use alternative agents.
Import ID
24
