Rukobia package insert
Interaction Color Code
Clinical Bottom Line
Administer standard doses
Drug 1
Drug 1 dose
600 mg BID
Drug 1 effect
Not studied
Drug 2
Drug 2 dose
8mg / 2mg to 24mg / 6mg once daily, individual dosing
Drug 2 effect
Buprenorphine Cmax increased 24%, AUC increased 30%, Cmin increased 39%. Norbuprenorphine Cmax increased 24%, AUC increased 39%, Cmin increased 39%
Import ID
12
