Rukobia package insert
Interaction Color Code
Clinical Bottom Line
Adjust dosing to avoid increased levels of rosuvastatin
Drug 1
Drug 1 dose
600 mg BID
Drug 1 effect
Not studied
Drug 2
Drug 2 dose
10 mg single dose
Drug 2 effect
Cmax increased 78%, AUC increased 69%
Clinical Effects
Increased statin exposure and risk of statin associated adverse events
Management
If co-adminstering, use lowest possible starting dose and monitor for statin associated adverse events
Import ID
3
