Abacavir

ARV U.S. Brand Name

Ziagen

ARV Abbreviation(s)

ABC

U.S. FDA Label

Abacavir Labeling (Package Insert)

ARV Class

Nucleoside reverse transcriptase inhibitors

First U.S. Approval

December 17, 1998

U.S. Manufacturer

ViiV Healthcare

Formulations

Strength	Formulation	Image	Description	Boosted
300 mg	Film-Coated Tablets	X	Yellow oblong tablet with "GX 623" imprint on both sides	No
240 mL	Oral Solution	X		No

Generic Available?

Yes

Other Reference Links

Abacavir Drug Information

FDCs

Abacavir / Dolutegravir / Lamivudine

Abacavir / Lamivudine

Abacavir / Lamivudine / Zidovudine

Assistance Programs

Displaying 1 - 8 of 8

	Interaction Color Code	Clinical Bottom Line	Clinical Effects	Drug 1 effect	Drug 2 dose	Drug 2 effect	Management
Tenofovir disoproxil fumarate ABC 740	Green: Administer standard doses	Administer standard doses		No significant change	300 mg x 1	No significant change
Abacavir AZT, ZDV 671	Green: Administer standard doses	Administer standard doses		Inconsistent effect across all dosing regimens; No effect on AUC with clinical abacavir dose of 300mg BID	200 mg TID, 300 mg BID	No significant change
Abacavir AZT, ZDV 670	Green: Administer standard doses	Administer standard doses		No significant change	300 mg x 1 dose	Zidovudine Cmax decreased 20%; AUC no significant change
Abacavir 3TC 669	Green: Administer standard doses	Administer standard doses		No significant change	150 mg x 1 dose	Lamivudine Cmax decreased 35%; AUC decreased 15%
Abacavir Ethanol 668	Green: Administer standard doses	Administer standard doses		Abacavir AUC increased 41%; half-life: increased 26%; Cmax increased 15%; T1 / 2 increased	0.7 g / kg body weight	No significant change
Abacavir MMF, MPA 667	Green: Administer standard doses	Administer standard doses		No significant change	500 mg BID x 16 weeks
Abacavir Methadone 666	Yellow: Adjust dosing	Adjust dosing to avoid reduced levels of methadone	Potential for decreased methadone effects (e.g., withdrawal)	No significant change	40 mg once daily; 90 mg once daily	Methadone clearance increased 22%	If coadministering monitor for signs and symptoms of methadone withdrawal. Some patients may require an increased methadone dose
Abacavir

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